IL18RAP (Gene)

Organism:

Homo sapiens

Synonyms:ACPL, CD218b, CDw218b, ENTREZ:8807, HGNC:5989, IL-18R-beta, IL-18RAcP, IL-18Rbeta, IL-1R-7, IL-1R7, IL-1RAcPL, IL18RAP, IL18RB, MIM:604509, NM_001393486, NM_001393487, NM_001393488, NM_001393489, NM_003853, NP_001380415, NP_001380416, NP_001380417, NP_001380418, NP_003844, XM_011512088, XM_017005173, XM_024453197, XM_024453198, XM_024453199, XM_024453200, XM_024453201, XP_011510390, XP_016860662, XP_024308965, XP_024308966, XP_024308967, XP_024308968, XP_024308969, XR_001739011, interleukin 18 receptor accessory protein

Omim:OMIM:604509

Id:ENSG00000115607

Hgnc:HGNC:5989

Entrez:8807

Ensembl:ENSG00000115607

Description:interleukin 18 receptor accessory protein

The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View IL18RAP's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with IL18RAP.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using IL18RAP.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for IL18RAP.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with IL18RAP.

Results found

Linked to

	Label	Description
	GSE189035 inositol 2 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE110178 5 V 0 TRANYLCYPROMINE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE154074 5 V 0 BLEOMYCIN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE77108 saha 6 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	T62-Spleen Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE166536 3 V 2 DOCETAXEL MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE202434,GSE202438 2 V 14 TALAZOPARIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE76425 0 V 12 LENALIDOMIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE147834 1 V 0 DOXORUBICIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE171837 3 V 1 BORTEZOMIB MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS

GSE189035 inositol 2 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE110178 5 V 0 TRANYLCYPROMINE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE154074 5 V 0 BLEOMYCIN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE77108 saha 6 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

T62-Spleen Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE166536 3 V 2 DOCETAXEL MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE202434,GSE202438 2 V 14 TALAZOPARIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE76425 0 V 12 LENALIDOMIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE147834 1 V 0 DOXORUBICIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE171837 3 V 1 BORTEZOMIB MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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