CNOT2 (Gene)

Organism:

Homo sapiens

Synonyms:CCR4-NOT transcription complex subunit 2, CDC36, CNOT2, ENTREZ:4848, HGNC:7878, HSPC131, IDNADFS, MIM:604909, NM_001199302, NM_001199303, NM_014515, NOT2, NOT2H, NP_001186231, NP_001186232, NP_055330, NR_037615, XM_006719429, XM_006719430, XM_006719432, XM_006719433, XM_011538399, XM_011538400, XM_017019348, XM_017019349, XM_017019350, XM_017019351, XM_017019352, XM_017019353, XM_017019354, XM_024448986, XM_024448987, XM_024448988, XP_006719492, XP_006719493, XP_006719495, XP_006719496, XP_011536701, XP_011536702, XP_016874837, XP_016874838, XP_016874839, XP_016874840, XP_016874841, XP_016874842, XP_016874843, XP_024304754, XP_024304755, XP_024304756, XR_001748718

Omim:OMIM:604909

Id:1f74b678-4515-5491-9b33-6fb0a3976e77

Hgnc:HGNC:7878

Entrez:4848

Ensembl:ENSG00000111596

Description:CCR4-NOT transcription complex subunit 2

This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CNOT2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CNOT2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CNOT2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CNOT2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CNOT2.

Results found

Linked to

	Label	Description
	GSE216043 7 V 9 CISPLATIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE159678 4 V 2 CHLOROQUINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE220097 4 V 1 ENZALUTAMIDE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE115395 2 V 4 ENZALUTAMIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE125014 enzalutamide prostate gland 1 v 5 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE199538 GSE199539 enzalutamide 2 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE119369 H10 inhibition 3 v 7 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE206931 WDR5 inhibition WIN 3 v 6 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE125014 1 V 5 ENZALUTAMIDE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE198930 prunetin AGS 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE216043 7 V 9 CISPLATIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE159678 4 V 2 CHLOROQUINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE220097 4 V 1 ENZALUTAMIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE115395 2 V 4 ENZALUTAMIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE125014 enzalutamide prostate gland 1 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE199538 GSE199539 enzalutamide 2 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE119369 H10 inhibition 3 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE206931 WDR5 inhibition WIN 3 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE125014 1 V 5 ENZALUTAMIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE198930 prunetin AGS 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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