IFNG (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:3458, HGNC:5438, IFG, IFI, IFNG, IMD69, MIM:147570, NM_000619, NP_000610, interferon gamma

Id:ENSG00000111537

Entrez:3458

Description:interferon gamma

This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View IFNG's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with IFNG.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using IFNG.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for IFNG.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with IFNG.

Results found

Linked to

	Label	Description
	GSE120612 7 V 5 ETOPOSIDE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE171837 3 V 1 BORTEZOMIB MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE193351 ruxolitinib 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE171837 0 V 3 BORTEZOMIB MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE119345 bexarotene T cell 0 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE119345 0 V 3 BEXAROTENE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE186810,GSE186813 2 V 0 FURIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE193351 1 V 2 RUXOLITINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE128885 deferiprone macrophage 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE135030 11 V 4 FLUDARABINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS

GSE120612 7 V 5 ETOPOSIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE171837 3 V 1 BORTEZOMIB MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE193351 ruxolitinib 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE171837 0 V 3 BORTEZOMIB MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE119345 bexarotene T cell 0 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE119345 0 V 3 BEXAROTENE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE186810,GSE186813 2 V 0 FURIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE193351 1 V 2 RUXOLITINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE128885 deferiprone macrophage 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE135030 11 V 4 FLUDARABINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.