NRXN2 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:9379, HGNC:8009, MIM:600566, NM_001376262, NM_001376263, NM_001376265, NM_001376266, NM_001376267, NM_015080, NM_138732, NM_138734, NP_001363191, NP_001363192, NP_001363194, NP_001363195, NP_001363196, NP_055895, NP_620060, NP_620063, NRXN2, XM_005274400, XM_011545370, XM_011545371, XM_011545373, XM_011545375, XM_011545385, XM_017018563, XM_017018564, XM_017018565, XM_017018566, XM_017018567, XM_017018568, XM_017018569, XM_017018570, XM_017018572, XM_017018573, XM_017018574, XM_017018575, XM_017018576, XM_017018577, XM_017018578, XM_024448770, XM_024448771, XM_024448772, XM_024448773, XM_024448774, XM_024448775, XM_024448776, XP_005274457, XP_011543672, XP_011543673, XP_011543675, XP_011543677, XP_011543687, XP_016874052, XP_016874053, XP_016874054, XP_016874055, XP_016874056, XP_016874057, XP_016874058, XP_016874059, XP_016874061, XP_016874062, XP_016874063, XP_016874064, XP_016874065, XP_016874066, XP_016874067, XP_024304538, XP_024304539, XP_024304540, XP_024304541, XP_024304542, XP_024304543, XP_024304544, XR_001748042, XR_001748043, XR_001748044, neurexin 2

Omim:OMIM:600566

Id:b3f9b1f4-6690-5f9e-964f-85154a175454

Hgnc:HGNC:8009

Entrez:9379

Ensembl:ENSG00000110076

Description:neurexin 2

This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992).[provided by RefSeq, Jun 2010]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NRXN2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with NRXN2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NRXN2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NRXN2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NRXN2.

Results found

Linked to

	Label	Description
	GSE131887 5 V 2 DOXYCYCLINE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE101239 5 V 6 VALPROIC ACID MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE205976 GSE205978 CEP83 knockout TIME 1 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE216988 GSE216989 decitabine 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE158456 2 V 3 FURIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE184210 0 V 1 GLUCAGON MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE130396 8 V 6 NERATINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE234148 HDAC inhibition 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	T62-Spleen Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE174498,GSE174500 2 V 8 ASPARAGINASE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS

GSE131887 5 V 2 DOXYCYCLINE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE101239 5 V 6 VALPROIC ACID MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE205976 GSE205978 CEP83 knockout TIME 1 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE216988 GSE216989 decitabine 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE158456 2 V 3 FURIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE184210 0 V 1 GLUCAGON MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE130396 8 V 6 NERATINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE234148 HDAC inhibition 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

T62-Spleen Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE174498,GSE174500 2 V 8 ASPARAGINASE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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