Synonyms:ENTREZ:3312, HEL-33, HEL-S-72p, HGNC:5241, HSC54, HSC70, HSC71, HSP71, HSP73, HSPA10, HSPA8, LAP-1, LAP1, MIM:600816, NIP71, NM_006597, NM_153201, NP_006588, NP_694881, XM_011542798, XP_011541100, heat shock protein family A (Hsp70) member 8
Omim:OMIM:600816
Id:02b6d634-8295-5ecd-987e-3beb0e897275
Hgnc:HGNC:5241
Description:heat shock protein family A (Hsp70) member 8
This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]