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HYAL4 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:CSHY, ENTREZ:23553, HGNC:5323, HYAL-4, HYAL4, MIM:604510, NM_012269, NP_036401, XM_011515990, XM_017011911, XM_024446703, XP_011514292, XP_016867400, XP_024302471, XR_002956416, hyaluronidase 4
Omim:OMIM:604510
Id:ENSG00000106302
Hgnc:HGNC:5323
Entrez:23553
Ensembl:ENSG00000106302
Description:hyaluronidase 4
This gene encodes a protein which is similar in structure to hyaluronidases but lacks hyaluronidase activity. The encoded protein acts as a chondroitin-sulfate-specific endo-beta-N-acetylgalactosaminidase; that is, it exhibits hydrolytic activity toward chondroitin sulfate chains and degrades them into oligosaccharides. Proteoglycans are formed by the covalent linkage of chondroitin sulfate chains to protein. Proteoglycans are ubiquitous components of the extracellular matrix of connective tissues and are also found at the surface of many cell types where they participate in a variety of cellular processes such as cell proliferation, differentiation, migration, cell-cell recognition, extracellular matrix deposition, and tissue morphogenesis. The expression of this gene is highest in testes and placenta. [provided by RefSeq, Apr 2019]

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Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HYAL4's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HYAL4.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HYAL4.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HYAL4.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HYAL4.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE172458 0 V 1 CISPLATIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

Preweaning Lethality, Incomplete Penetrance (MP:0011110)

Gene Set (Entity type)

A Gene Set from KOMP2

Gene Set

GSE173116 GSE173118 ML-7 3 v 10 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE210682 2 V 1 METHADONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE123825 2 V 3 GLUTAMINE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE164508 1 V 0 BORTEZOMIB MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE245270 2 V 5 ISOPROTERENOL HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE129370 0 V 1 ETHANOL MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE199034 1 V 0 PIRFENIDONE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 6 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE172458 0 V 1 CISPLATIN HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    Preweaning Lethality, Incomplete Penetrance (MP:0011110)

    Gene Set (Entity type)

    A Gene Set from KOMP2

  • Gene Set

    GSE173116 GSE173118 ML-7 3 v 10 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE210682 2 V 1 METHADONE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE123825 2 V 3 GLUTAMINE MOUSE DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE164508 1 V 0 BORTEZOMIB MOUSE DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE245270 2 V 5 ISOPROTERENOL HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE129370 0 V 1 ETHANOL MOUSE DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE199034 1 V 0 PIRFENIDONE MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 6 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.