Synonyms:C19orf2, ENTREZ:8725, HGNC:13236, MIM:603494, NM_001252641, NM_003796, NM_134447, NNX3, NP_001239570, NP_003787, NR_045557, PPP1R19, RMP, URI, URI1 prefoldin like chaperone, URI1, XM_005259362, XM_005259363, XM_011527435, XM_024451751, XP_005259419, XP_005259420, XP_011525737, XP_024307519
Omim:OMIM:603494
Id:ENSG00000105176
Hgnc:HGNC:13236
Description:URI1 prefoldin like chaperone
This gene encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. This gene may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22. [provided by RefSeq, Nov 2011]