DKK4 (Gene)

Organism:

Homo sapiens

Synonyms:DKK-4, DKK4, ENTREZ:27121, HGNC:2894, MIM:605417, NM_014420, NP_055235, XM_011544488, XM_017013316, XP_011542790, XP_016868805, dickkopf WNT signaling pathway inhibitor 4

Omim:OMIM:605417

Id:ENSG00000104371

Hgnc:HGNC:2894

Entrez:27121

Ensembl:ENSG00000104371

Description:dickkopf Wnt signaling pathway inhibitor 4

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co-receptor and the co-factor kremen 2. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View DKK4's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with DKK4.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using DKK4.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for DKK4.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DKK4.

Results found

Linked to

	Label	Description
	GSE184902 4 V 0 ADIPONECTIN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE113215 GSE113217 KIT inhibition 2 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE202434,GSE202438 8 V 14 TALAZOPARIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE205332 1 V 0 QUEUINE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE202434 GSE202438 talazoparib 6 v 14 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE250534 4 V 1 CABERGOLINE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE236896 GSE237665 DNMT EZH2 inhibition 1 v 8 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE171269 1 V 3 PIOGLITAZONE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE202434,GSE202438 6 V 14 TALAZOPARIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE112714 Ctnnb1 knockout 2 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE184902 4 V 0 ADIPONECTIN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE113215 GSE113217 KIT inhibition 2 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE202434,GSE202438 8 V 14 TALAZOPARIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE205332 1 V 0 QUEUINE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE202434 GSE202438 talazoparib 6 v 14 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE250534 4 V 1 CABERGOLINE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE236896 GSE237665 DNMT EZH2 inhibition 1 v 8 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE171269 1 V 3 PIOGLITAZONE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE202434,GSE202438 6 V 14 TALAZOPARIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE112714 Ctnnb1 knockout 2 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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