SETD6 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:79918, HGNC:26116, MIM:616424, NM_001160305, NM_024860, NP_001153777, NP_079136, NR_134583, SET domain containing 6, protein lysine methyltransferase, SETD6, XM_011523336, XP_011521638, XR_001751988, XR_001751989, XR_243429, XR_933436, XR_933437

Omim:OMIM:616424

Id:ENSG00000103037

Hgnc:HGNC:26116

Entrez:79918

Ensembl:ENSG00000103037

Description:SET domain containing 6, protein lysine methyltransferase

This gene encodes a methyltransferase that adds a methyl group to the histone H2AZ, which is involved in nuclear receptor-dependent transcription. The protein also interacts with several endogenous proteins which are involved in nuclear hormone receptor signaling. A related pseudogene is located on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SETD6's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SETD6.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SETD6.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SETD6.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SETD6.

Results found

Linked to

	Label	Description
	GSE186471 1 V 2 CARNOSOL HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE208634 1 V 2 DOXYCYCLINE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE226525 GSE226527 HNRNPH2 knockout 6 v 5 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE229973 3 V 2 CISPLATIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE120612 4 V 1 ETOPOSIDE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE146612 2 V 0 AMIODARONE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE82110,GSE82299 1 V 0 ACRIFLAVINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE201309 5 V 0 MATRINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE193541 nifurtimox A-549 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE201309 4 V 2 MATRINE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS

GSE186471 1 V 2 CARNOSOL HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE208634 1 V 2 DOXYCYCLINE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE226525 GSE226527 HNRNPH2 knockout 6 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE229973 3 V 2 CISPLATIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE120612 4 V 1 ETOPOSIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE146612 2 V 0 AMIODARONE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE82110,GSE82299 1 V 0 ACRIFLAVINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE201309 5 V 0 MATRINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE193541 nifurtimox A-549 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE201309 4 V 2 MATRINE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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