CCL22 (Gene)

Organism:

Homo sapiens

Synonyms:A-152E5.1, ABCD-1, C-C motif chemokine ligand 22, CCL22, DC/B-CK, ENTREZ:6367, HGNC:10621, MDC, MIM:602957, NM_002990, NP_002981, SCYA22, STCP-1

Omim:OMIM:602957

Id:ENSG00000102962

Hgnc:HGNC:10621

Entrez:6367

Ensembl:ENSG00000102962

Description:C-C motif chemokine ligand 22

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Sep 2014]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CCL22's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CCL22.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CCL22.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CCL22.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CCL22.

Results found

Linked to

	Label	Description
	GSE154074 5 V 0 BLEOMYCIN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE216540 1 V 6 FULVESTRANT HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE190937 AHCY MAT2A knockout Rael 2 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE164521 0 V 1 NITRIC OXIDE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE155162 GSE155169 buparlisib 1 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE56010 adenosine 4 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE135030 11 V 10 FLUDARABINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE229070,GSE229071 0 V 2 SOTORASIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE135030 8 V 5 FLUDARABINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE190937 AHCY MAT2A knockout Rael 4 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE154074 5 V 0 BLEOMYCIN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE216540 1 V 6 FULVESTRANT HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE190937 AHCY MAT2A knockout Rael 2 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE164521 0 V 1 NITRIC OXIDE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE155162 GSE155169 buparlisib 1 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE56010 adenosine 4 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE135030 11 V 10 FLUDARABINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE229070,GSE229071 0 V 2 SOTORASIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE135030 8 V 5 FLUDARABINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE190937 AHCY MAT2A knockout Rael 4 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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