LYRM1 (Gene)

Organism:

Homo sapiens

Synonyms:A211C6.1, ENTREZ:57149, HGNC:25074, LYR motif containing 1, LYRM1, MIM:614709, NM_001128301, NM_001128302, NM_001302835, NM_001302836, NM_001369631, NM_001369632, NM_001369633, NM_001369634, NM_001369635, NM_001369636, NM_001369637, NM_001369638, NM_001369639, NM_001369641, NM_001369642, NM_001369644, NM_001369645, NM_020424, NP_001121773, NP_001121774, NP_001289764, NP_001289765, NP_001356560, NP_001356561, NP_001356562, NP_001356563, NP_001356564, NP_001356565, NP_001356566, NP_001356567, NP_001356568, NP_001356570, NP_001356571, NP_001356573, NP_001356574, NP_065157, NR_126516, NR_126520, NR_126521, NR_126527, NR_126528, NR_161425, NR_161426, NR_161427, NR_161429, NR_161430, NR_161431, NR_161432, XM_011545900, XM_011545901, XM_011545908, XM_017023475, XM_017023476, XM_017023477, XM_017023478, XM_017023480, XP_011544202, XP_011544203, XP_011544210, XP_016878964, XP_016878965, XP_016878966, XP_016878967, XP_016878969, XR_950823

Omim:OMIM:614709

Id:ENSG00000102897

Hgnc:HGNC:25074

Entrez:57149

Ensembl:ENSG00000102897

Description:LYR motif containing 1

The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LYRM1's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with LYRM1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LYRM1.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LYRM1.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LYRM1.

Results found

Linked to

	Label	Description
	GSE240439 decitabine 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE146358 dopamine 3 v 7 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE192750 adipose overexpression Grunt Fin PNMR OE 1 v 9 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE93156 idelalisib B cell 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE206927 PPARG knockdown endothelial cell 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE125862 2 V 1 DEXAMETHASONE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE82110,GSE82299 1 V 0 ACRIFLAVINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE176403 GSE176404 LSD1 inhibition 1 v 4 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE146358 dopamine 5 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE158552 BRD4 inhibition 2 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE240439 decitabine 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE146358 dopamine 3 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE192750 adipose overexpression Grunt Fin PNMR OE 1 v 9 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE93156 idelalisib B cell 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE206927 PPARG knockdown endothelial cell 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE125862 2 V 1 DEXAMETHASONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE82110,GSE82299 1 V 0 ACRIFLAVINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE176403 GSE176404 LSD1 inhibition 1 v 4 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE146358 dopamine 5 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE158552 BRD4 inhibition 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.