PDYN (Gene)

Organism:

Homo sapiens

Synonyms:ADCA, ENTREZ:5173, HGNC:8820, MIM:131340, NM_001190892, NM_001190898, NM_001190899, NM_001190900, NM_024411, NP_001177821, NP_001177827, NP_001177828, NP_001177829, NP_077722, PDYN, PENKB, SCA23, XM_011529244, XM_011529245, XM_011529246, XM_011529247, XM_011529248, XM_011529249, XM_011529250, XM_017027878, XP_011527546, XP_011527547, XP_011527548, XP_011527549, XP_011527550, XP_011527551, XP_011527552, XP_016883367, prodynorphin

Id:ENSG00000101327

Entrez:5173

Ensembl:ENSG00000101327

Description:prodynorphin

The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PDYN's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PDYN.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PDYN.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PDYN.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PDYN.

Results found

Linked to

	Label	Description
	GSE131887 5 V 2 DOXYCYCLINE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE212330 azacitidine 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE184210 0 V 1 GLUCAGON MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE146612 2 V 0 AMIODARONE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE154074 5 V 0 BLEOMYCIN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE213845 EZH2 inhibition 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE213845 EZH2 inhibition 4 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE212330 1 V 0 AZACITIDINE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE154074 1 V 0 BLEOMYCIN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE164757,GSE164759 4 V 3 TRAMETINIB MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS

GSE131887 5 V 2 DOXYCYCLINE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE212330 azacitidine 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE184210 0 V 1 GLUCAGON MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE146612 2 V 0 AMIODARONE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE154074 5 V 0 BLEOMYCIN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE213845 EZH2 inhibition 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE213845 EZH2 inhibition 4 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE212330 1 V 0 AZACITIDINE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE154074 1 V 0 BLEOMYCIN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE164757,GSE164759 4 V 3 TRAMETINIB MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.