Synonyms:ASPIC, ASPIC1, CEP-68, CEP68, CRTAC1, ENTREZ:55118, HGNC:14882, LOTUS, MIM:606276, NM_001206528, NM_018058, NP_001193457, NP_060528, XM_005269938, XM_011539917, XM_017016366, XM_017016367, XP_005269995, XP_011538219, XP_016871855, XP_016871856, cartilage acidic protein 1
Omim:OMIM:606276
Id:0438a78c-6645-593e-95aa-98b396932fce
Hgnc:HGNC:14882
Description:cartilage acidic protein 1
This gene encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]