SIRPG (Gene)

Organism:

Homo sapiens

Synonyms:CD172g, ENTREZ:55423, HGNC:15757, MIM:605466, NM_001039508, NM_018556, NM_080816, NP_001034597, NP_061026, NP_543006, SIRP-B2, SIRPB2, SIRPG, SIRPgamma, XM_005260749, XM_011529286, XM_011529287, XP_005260806, XP_011527588, XP_011527589, bA77C3.1, signal regulatory protein gamma

Omim:OMIM:605466

Id:ea503b46-ff8c-522b-aa78-c6a9ecb63c48

Hgnc:HGNC:15757

Entrez:55423

Ensembl:ENSG00000089012

Description:signal regulatory protein gamma

The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SIRPG's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SIRPG.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SIRPG.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SIRPG.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SIRPG.

Results found

Linked to

	Label	Description
	GSE195568 palbociclib 2 v 10 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE114883 0 V 5 ROMIDEPSIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE125862 2 V 1 DEXAMETHASONE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE196035 GSE196037 MEN1 inhibition 6 v 10 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE214931 temozolomide 4 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE120612 4 V 3 ETOPOSIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE182680,GSE182683 7 V 2 DEXAMETHASONE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE182680 GSE182683 dexamethasone 7 v 11 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE155162 GSE155169 buparlisib 1 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE195568 2 V 10 PALBOCICLIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS

GSE195568 palbociclib 2 v 10 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE114883 0 V 5 ROMIDEPSIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE125862 2 V 1 DEXAMETHASONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE196035 GSE196037 MEN1 inhibition 6 v 10 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE214931 temozolomide 4 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE120612 4 V 3 ETOPOSIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE182680,GSE182683 7 V 2 DEXAMETHASONE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE182680 GSE182683 dexamethasone 7 v 11 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE155162 GSE155169 buparlisib 1 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE195568 2 V 10 PALBOCICLIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.