RBFOX1 (Gene)

Organism:

Homo sapiens

Synonyms:2BP1, A2BP1, ENTREZ:54715, FOX-1, FOX1, HGNC:18222, HRNBP1, MIM:605104, NM_001142333, NM_001142334, NM_001308117, NM_001364800, NM_018723, NM_145891, NM_145892, NM_145893, NP_001135805, NP_001135806, NP_001295046, NP_001351729, NP_061193, NP_665898, NP_665899, NP_665900, RBFOX1, RNA binding fox-1 homolog 1, XM_005255386, XM_005255387, XM_005255390, XM_005255391, XM_005255394, XM_011522546, XM_011522547, XM_011522548, XM_017023318, XM_017023319, XM_017023320, XM_017023321, XM_017023322, XM_017023323, XM_017023324, XM_017023326, XM_017023327, XM_017023328, XM_017023329, XM_017023330, XM_017023331, XM_017023332, XM_017023333, XM_017023334, XM_017023336, XM_017023337, XM_017023338, XM_017023340, XM_017023341, XM_017023342, XM_024450303, XM_024450304, XM_024450305, XM_024450306, XM_024450307, XM_024450308, XM_024450309, XM_024450310, XM_024450311, XM_024450312, XM_024450313, XM_024450314, XM_024450315, XM_024450316, XP_005255443, XP_005255444, XP_005255447, XP_005255448, XP_005255451, XP_011520848, XP_011520849, XP_011520850, XP_016878807, XP_016878808, XP_016878809, XP_016878810, XP_016878811, XP_016878812, XP_016878813, XP_016878815, XP_016878816, XP_016878817, XP_016878818, XP_016878819, XP_016878820, XP_016878821, XP_016878822, XP_016878823, XP_016878825, XP_016878826, XP_016878827, XP_016878829, XP_016878830, XP_016878831, XP_024306071, XP_024306072, XP_024306073, XP_024306074, XP_024306075, XP_024306076, XP_024306077, XP_024306078, XP_024306079, XP_024306080, XP_024306081, XP_024306082, XP_024306083, XP_024306084

Omim:OMIM:605104

Nci:C98194

Id:ENSG00000078328

Hgnc:HGNC:18222

Entrez:54715

Ensembl:ENSG00000078328

Description:RNA binding fox-1 homolog 1

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View RBFOX1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with RBFOX1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using RBFOX1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for RBFOX1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with RBFOX1.

Results found

Linked to

	Label	Description
	GSE131887 5 V 2 DOXYCYCLINE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE168401 2 V 0 HARMINE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE234647 1 V 3 REGORAFENIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE216273,GSE216292 14 V 1 PALBOCICLIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE212312 FBXW7 knockout Reh 1 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE56010 adenosine 4 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE92965 0 V 1 TAMOXIFEN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE218580 1 V 4 FENTANYL MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE184902 4 V 1 ADIPONECTIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE135030 8 V 5 FLUDARABINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS