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EPHA8 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:EEK, EK3, ENTREZ:2046, EPH receptor A8, EPHA8, HEK3, HGNC:3391, MIM:176945, NM_001006943, NM_020526, NP_001006944, NP_065387, XM_011540969, XM_011540970, XM_011540972, XM_011540973, XM_011540975, XM_024453892, XP_011539271, XP_011539272, XP_011539274, XP_011539275, XP_011539277, XP_024309660, XR_946576
Omim:OMIM:176945
Id:ENSG00000070886
Hgnc:HGNC:3391
Entrez:2046
Ensembl:ENSG00000070886
Description:EPH receptor A8
This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. [provided by RefSeq, Jul 2008]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View EPHA8's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with EPHA8.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using EPHA8.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for EPHA8.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with EPHA8.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE135514 8 V 7 DASATINIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE187006 3 V 2 VALPROIC ACID HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE57871 5 V 9 VORINOSTAT HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE213588 10 V 6 TRAMETINIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE173201 0 V 1 CISPLATIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE137325 2 V 0 COPANLISIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE77108 saha 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE77108 saha 6 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE77108 saha 5 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE147876 GSE147877 enzalutamide MR42D 4 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE135514 8 V 7 DASATINIB HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE187006 3 V 2 VALPROIC ACID HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE57871 5 V 9 VORINOSTAT HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213588 10 V 6 TRAMETINIB HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE173201 0 V 1 CISPLATIN HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE137325 2 V 0 COPANLISIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE77108 saha 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE77108 saha 6 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE77108 saha 5 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE147876 GSE147877 enzalutamide MR42D 4 v 7 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.