CFDE Workbench
DataKnowledgeCloudtrainingcoordination
CFDE Workbench

MNT (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:4335, HGNC:7188, MAD6, MAX network transcriptional repressor, MIM:603039, MNT, MXD6, NM_020310, NP_064706, ROX, XM_011523868, XM_011523869, XM_017024654, XM_024450758, XM_024450759, XP_011522170, XP_011522171, XP_016880143, XP_024306526, XP_024306527, bHLHd3, lncRNA-HAL
Omim:OMIM:603039
Id:ENSG00000070444
Hgnc:HGNC:7188
Entrez:4335
Ensembl:ENSG00000070444
Description:MAX network transcriptional repressor
The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MNT's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with MNT.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MNT.

Submit
Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MNT.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MNT.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE226249 pirfenidone HL 0 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE192860 0 V 1 TRIFLUOPERAZINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE67266 7 V 3 ETOPOSIDE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE230634 PARP inhibition 0 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE119369 H10 inhibition 1 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE236896 GSE237665 DNMT EZH2 inhibition 1 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE252944 AKT inhibition 10 v 15 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE121425 GSE121426 LSD1 inhibition SET-2 2 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE125157 1 V 0 PICEATANNOL MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE135352 6 V 4 NAPABUCASIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE226249 pirfenidone HL 0 v 7 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE192860 0 V 1 TRIFLUOPERAZINE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE67266 7 V 3 ETOPOSIDE MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE230634 PARP inhibition 0 v 4 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE119369 H10 inhibition 1 v 5 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE236896 GSE237665 DNMT EZH2 inhibition 1 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE252944 AKT inhibition 10 v 15 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE121425 GSE121426 LSD1 inhibition SET-2 2 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE125157 1 V 0 PICEATANNOL MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE135352 6 V 4 NAPABUCASIN HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

    • DISPLAY PER PAGE
    CFDE Workbench
    Report a bug
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    @CFDE Workbench 2026
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.