POU1F1 (Gene)

Organism:

Homo sapiens

Synonyms:CPHD1, ENTREZ:5449, GHF-1, HGNC:9210, MIM:173110, NM_000306, NM_001122757, NP_000297, NP_001116229, PIT1, POU class 1 homeobox 1, POU1F1, POU1F1a, Pit-1

Id:ENSG00000064835

Entrez:5449

Ensembl:ENSG00000064835

Description:POU class 1 homeobox 1

This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View POU1F1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with POU1F1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using POU1F1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for POU1F1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with POU1F1.

Results found

Linked to

	Label	Description
	GSE173201 0 V 1 CISPLATIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE197555 trametinib A-549 NCI-H460 1 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE143782 calcitriol 3 v 11 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE208350 H-7 Huh-7 JHH-7 0 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE171837 3 V 1 BORTEZOMIB MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE197555 1 V 2 TRAMETINIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE208350 H-7 Huh-7 JHH-7 0 v 8 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE208350 H-7 Huh-7 JHH-7 0 v 6 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE158458 2 V 3 SORAFENIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE143782 3 V 11 CALCITRIOL HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS

GSE173201 0 V 1 CISPLATIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE197555 trametinib A-549 NCI-H460 1 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE143782 calcitriol 3 v 11 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE208350 H-7 Huh-7 JHH-7 0 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE171837 3 V 1 BORTEZOMIB MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE197555 1 V 2 TRAMETINIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE208350 H-7 Huh-7 JHH-7 0 v 8 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE208350 H-7 Huh-7 JHH-7 0 v 6 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE158458 2 V 3 SORAFENIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE143782 3 V 11 CALCITRIOL HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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