PSD (Gene)

Organism:

Homo sapiens

Synonyms:EFA6, EFA6A, ENTREZ:5662, HGNC:9507, MIM:602327, NM_001270965, NM_001270966, NM_002779, NP_001257894, NP_001257895, NP_002770, NR_073110, PSD, PSD1, TYL, XM_011539968, XM_011539969, XM_017016433, XM_017016434, XP_011538270, XP_011538271, XP_016871922, XP_016871923, pleckstrin and Sec7 domain containing

Id:ENSG00000059915

Entrez:5662

Ensembl:ENSG00000059915

Description:pleckstrin and Sec7 domain containing

This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PSD's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PSD.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PSD.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PSD.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PSD.

Results found

Linked to

	Label	Description
	GSE114883 romidepsin T cell 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE128240 0 V 1 CYCLOPHOSPHAMIDE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE111247 temozolomide LN-308 2 v 13 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE125782 3 V 1 GLUTAMINE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE166315 1 V 0 DOCETAXEL MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE153189 1 V 3 INTERFERON GAMMA MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE145650 COX2 inhibition 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE80446 2 V 1 ANAKINRA MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE157960 0 V 3 PROGESTERONE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE147662 2 V 5 NICOTINAMIDE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS

GSE114883 romidepsin T cell 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE128240 0 V 1 CYCLOPHOSPHAMIDE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE111247 temozolomide LN-308 2 v 13 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE125782 3 V 1 GLUTAMINE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE166315 1 V 0 DOCETAXEL MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE153189 1 V 3 INTERFERON GAMMA MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE145650 COX2 inhibition 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE80446 2 V 1 ANAKINRA MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE157960 0 V 3 PROGESTERONE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE147662 2 V 5 NICOTINAMIDE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.