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C6 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:C6, ENTREZ:729, HGNC:1339, MIM:217050, NM_000065, NM_001115131, NP_000056, NP_001108603, XM_006714496, XM_011514114, XM_011514115, XM_011514116, XM_011514117, XM_011514118, XM_011514119, XM_011514121, XM_017009818, XM_017009819, XP_006714559, XP_011512416, XP_011512417, XP_011512418, XP_011512419, XP_011512420, XP_011512421, XP_011512423, XP_016865307, XP_016865308, complement C6
Omim:OMIM:217050
Id:eac52afa-ad4a-50fd-b7fd-1b7622e5fa0e
Hgnc:HGNC:1339
Entrez:729
Ensembl:ENSG00000039537
Description:complement C6
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View C6's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with C6.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using C6.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for C6.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with C6.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE144443 0 V 6 NICOTINAMIDE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE216273 GSE216292 palbociclib 14 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE143782 calcitriol 7 v 11 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE109913 1 V 2 BLEOMYCIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE208350 H-7 Huh-7 JHH-7 0 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE220520 3 V 4 ETHANOL MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE155031 catechin SH-SY5Y 5 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE208350 H-7 Huh-7 JHH-7 4 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE203267 ALKBH5 knockdown Ramia 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE185200 GSE185202 L-13 Ali-BL 0 v 9 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE144443 0 V 6 NICOTINAMIDE MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE216273 GSE216292 palbociclib 14 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE143782 calcitriol 7 v 11 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE109913 1 V 2 BLEOMYCIN MOUSE DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE208350 H-7 Huh-7 JHH-7 0 v 3 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE220520 3 V 4 ETHANOL MOUSE DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE155031 catechin SH-SY5Y 5 v 3 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE208350 H-7 Huh-7 JHH-7 4 v 3 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE203267 ALKBH5 knockdown Ramia 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE185200 GSE185202 L-13 Ali-BL 0 v 9 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.