ATP6V0A1 (Gene)

Organism:

Homo sapiens

Synonyms:ATP6N1, ATP6N1A, ATP6V0A1, ATPase H+ transporting V0 subunit a1, ENTREZ:535, HGNC:865, MIM:192130, NM_001130020, NM_001130021, NM_001378522, NM_001378523, NM_001378530, NM_001378531, NM_001378532, NM_001378533, NM_001378534, NM_001378535, NM_001378536, NM_001378537, NM_001378538, NM_001378539, NM_001378540, NM_001378541, NM_001378542, NM_001378543, NM_001378544, NM_001378545, NM_001378546, NM_001378547, NM_001378548, NM_001378549, NM_001378550, NM_001378551, NM_001378552, NM_001378554, NM_001378556, NM_001378557, NM_005177, NP_001123492, NP_001123493, NP_001365451, NP_001365452, NP_001365459, NP_001365460, NP_001365461, NP_001365462, NP_001365463, NP_001365464, NP_001365465, NP_001365466, NP_001365467, NP_001365468, NP_001365469, NP_001365470, NP_001365471, NP_001365472, NP_001365473, NP_001365474, NP_001365475, NP_001365476, NP_001365477, NP_001365478, NP_001365479, NP_001365480, NP_001365481, NP_001365483, NP_001365485, NP_001365486, NP_005168, Stv1, VPP1, Vph1, XM_017024772, XM_017024773, XM_017024774, XP_016880261, XP_016880262, XP_016880263, XR_001752538, XR_001752539, XR_001752540, XR_002958025, XR_002958026, XR_002958027, XR_002958028, XR_002958029, XR_002958030, XR_934483, XR_934484, a1

Omim:OMIM:192130

Id:ENSG00000033627

Hgnc:HGNC:865

Entrez:535

Ensembl:ENSG00000033627

Description:ATPase H+ transporting V0 subunit a1

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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Results found

Linked to

	Label	Description
	GSE145990 1 V 0 IBRUTINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE114883 romidepsin T cell 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE186471 1 V 2 CARNOSOL HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE203362 0 V 1 ENZALUTAMIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE138789 metformin 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE202434 GSE202438 talazoparib 6 v 11 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE158834 0 V 3 PALMITIC ACID HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE152441,GSE152442 6 V 4 FOLIC ACID HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE48812 sulforaphane 4 v 10 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE205976 GSE205978 CEP83 knockout TIME 1 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE145990 1 V 0 IBRUTINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE114883 romidepsin T cell 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE186471 1 V 2 CARNOSOL HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE203362 0 V 1 ENZALUTAMIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE138789 metformin 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE202434 GSE202438 talazoparib 6 v 11 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE158834 0 V 3 PALMITIC ACID HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE152441,GSE152442 6 V 4 FOLIC ACID HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE48812 sulforaphane 4 v 10 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE205976 GSE205978 CEP83 knockout TIME 1 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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