Synonyms:ECGF, ECGF1, ENTREZ:1890, HGNC:3148, MEDPS1, MIM:131222, MNGIE, MTDPS1, NM_001113755, NM_001113756, NM_001257988, NM_001257989, NM_001953, NP_001107227, NP_001107228, NP_001244917, NP_001244918, NP_001944, PDECGF, TP, TYMP, hPD-ECGF, thymidine phosphorylase
Omim:OMIM:131222
Id:85b15dc9-0fc0-5c82-8ae5-47f7a1ab9b52
Hgnc:HGNC:3148
Description:thymidine phosphorylase
This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]