NRXN3 (Gene)

Organism:

Homo sapiens

Synonyms:C14orf60, ENTREZ:9369, HGNC:8010, MIM:600567, NM_001105250, NM_001272020, NM_001330195, NM_001366425, NM_001366426, NM_004796, NM_138970, NP_001098720, NP_001258949, NP_001317124, NP_001353354, NP_001353355, NP_004787, NP_620426, NRXN3, NR_073546, NR_073547, NR_158973, NR_158974, NR_158975, XM_005268218, XM_006720322, XM_011537363, XM_011537364, XM_011537365, XM_011537366, XM_011537367, XM_011537368, XM_011537369, XM_011537370, XM_011537371, XM_011537372, XM_011537373, XM_017021790, XM_017021791, XM_017021792, XM_017021793, XM_017021794, XM_017021796, XM_017021797, XM_017021798, XM_017021799, XM_017021800, XM_017021801, XM_017021804, XM_017021805, XM_017021807, XM_024449750, XM_024449751, XM_024449752, XM_024449753, XP_005268275, XP_006720385, XP_011535665, XP_011535666, XP_011535667, XP_011535668, XP_011535669, XP_011535670, XP_011535671, XP_011535672, XP_011535673, XP_011535674, XP_011535675, XP_016877279, XP_016877280, XP_016877281, XP_016877282, XP_016877283, XP_016877285, XP_016877286, XP_016877287, XP_016877288, XP_016877289, XP_016877290, XP_016877293, XP_016877294, XP_016877296, XP_024305518, XP_024305519, XP_024305520, XP_024305521, XR_001750599, XR_001750600, XR_001750602, XR_001750604, XR_001750605, XR_001750606, XR_001750607, XR_001750609, XR_001750610, XR_002957572, XR_943561, XR_943563, neurexin 3

Omim:OMIM:600567

Nci:C113536

Id:ENSG00000021645

Hgnc:HGNC:8010

Entrez:9369

Ensembl:ENSG00000021645

Description:neurexin 3

This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NRXN3's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with NRXN3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NRXN3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NRXN3.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NRXN3.

Results found

Linked to

	Label	Description
	GSE172016 2 V 5 PACLITAXEL HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE216043 10 V 5 CISPLATIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE158834 ADIPOR2 knockout HEK293 1 v 6 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE97616 GSE97617 NOK overexpression HEK RNA Small Interfering 7 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE265788 IDH1 inhibition RNA-Directed DNA Polymerase 7 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE135030 3 V 10 FLUDARABINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE158834 0 V 4 PALMITIC ACID HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE113655 phenol 1 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE158834 ADIPOR2 knockout HEK293 10 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE165334 2 V 0 DABRAFENIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS