Synonyms:CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, CDK11A, ENTREZ:728642, HGNC:1730, MIM:116951, NM_001313896, NM_001313982, NM_024011, NM_033527, NM_033529, NM_033532, NM_033534, NP_001300825, NP_001300911, NP_076916, NP_277071, NR_132739, NR_132740, PITSLRE, cyclin dependent kinase 11A, p58GTA
Omim:OMIM:116951
Id:ENSG00000008128
Hgnc:HGNC:1730
Description:cyclin dependent kinase 11A
This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]