Abemaciclib (Compound)

Synonyms:Abemaciclib, 1231929-97-7, LY2835219, Verzenio, LY2835219 free base, LY-2835219, UNII-60UAB198HK, Verzenios, N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine, 60UAB198HK

Pubchem:PUBCHEM:46220502

Id:86d7c3c8-e15e-534c-9e40-8fc54422fb63

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Abemaciclib's neighborhood in the knowledge graph.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for Abemaciclib.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with Abemaciclib.

Results found

Linked to

	Label	Description
	BRD-K33622447-066-01-9 Substance (Entity type)	A Substance
	Abemaciclib negatively regulates CD55 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	Abemaciclib negatively regulates DLGAP5 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	Abemaciclib negatively regulates RPS4Y1 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	Abemaciclib negatively regulates ADI1 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	Abemaciclib bioactivity Glycogen synthase kinase-3 beta Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from IDG
	Abemaciclib bioactivity Cyclin-dependent kinase 6 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from IDG
	Abemaciclib bioactivity Calcium/calmodulin-dependent protein kinase type II subunit gamma Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from IDG
	Abemaciclib negatively regulates HSPA2 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	Abemaciclib positively regulates GALNT14 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS

BRD-K33622447-066-01-9

Substance (Entity type)

A Substance

Abemaciclib negatively regulates CD55

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from LINCS

Abemaciclib negatively regulates DLGAP5

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from LINCS

Abemaciclib negatively regulates RPS4Y1

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from LINCS

Abemaciclib negatively regulates ADI1

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from LINCS

Abemaciclib bioactivity Glycogen synthase kinase-3 beta

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from IDG

Abemaciclib bioactivity Cyclin-dependent kinase 6

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from IDG

Abemaciclib bioactivity Calcium/calmodulin-dependent protein kinase type II subunit gamma

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from IDG

Abemaciclib negatively regulates HSPA2

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from LINCS

Abemaciclib positively regulates GALNT14

Knowledge Graph Assertion (Entity type)

A Knowledge Graph Assertion from LINCS

DISPLAY PER PAGE

CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.