Trametinib (Compound)

Synonyms:Trametinib, 871700-17-3, GSK1120212, Mekinist, GSK-1120212, JTP 74057, JTP-74057, GSK 1120212, Trametinib (GSK1120212), N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide

Pubchem:PUBCHEM:11707110

Id:cb6e8193-e8b4-5b92-adc7-eda87665e851

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Trametinib's neighborhood in the knowledge graph.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for Trametinib.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with Trametinib.

Results found

Linked to

	Label	Description
	BRD-K12343256-001-18-8 Substance (Entity type)	A Substance
	Trametinib in similarity relationship with 2-(2-chloro-4-iodophenylamino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	SID11113946 in similarity relationship with Trametinib Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	PD-325901 in similarity relationship with Trametinib Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	Trametinib indication Malignant melanoma with BRAF V600E mutation Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from IDG
	Trametinib negatively regulates TMEM158 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	Trametinib negatively regulates SLC20A1 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	Trametinib negatively regulates DUSP4 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	Trametinib positively regulates KRT14 Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS
	Trametinib in similarity relationship with 3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamide Knowledge Graph Assertion (Entity type)	A Knowledge Graph Assertion from LINCS

BRD-K12343256-001-18-8

Substance (Entity type)

A Substance

Trametinib in similarity relationship with 2-(2-chloro-4-iodophenylamino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide

Knowledge Graph Assertion (Entity type)