SNT355.CFGL.684 (Collection)

Has Time Series Data:0
Description:This dataset was generated using the 10x Genomics Visium Spatial Gene Expression assay on a 10-μm section of fresh frozen subcutaneous white adipose tissue resected during bariatric surgery on a high-BMI (39.67) female aged 42 years. Age- and obesity-related dysfunction of adipose tissue has been linked to cellular senescence, systemic inflammation, and metabolic disease. Much remains to be discovered, however, about the spatial distribution of senescence-associated niches in human adipose tissue. 2- and 3-dimensional characterization of senescence is aided by the use of spatial omics advances such as Visium, which allows whole-transcriptome spatial profiling of RNA from tissues with 55-μm resolution. In situ reverse transcription generates cDNA molecules in the tissue, which are released, captured, and extended on spatially-barcoded oligonucleotide spots on the glass slide beneath the tissue. Barcoded cDNA is used to generate sequencing libraries, reads from which can be spatially mapped to the overlaid tissue area where each read originated.
Creation Time:2024-03-19 13:10:12.561000
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A 8.34 GB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

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A 3.66 GB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

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A 947 B file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

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A 541 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

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A 1.16 GB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

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A 587 B file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

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A 1.76 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

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A 102 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

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A 991 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

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A 2.00 B file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

  • File

    A 8.34 GB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project


  • File

    A 3.66 GB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project


  • File

    A 947 B file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project


  • File

    A 541 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project


  • File

    A 1.16 GB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project


  • File

    A 587 B file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project


  • File

    A 1.76 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project


  • File

    A 102 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project


  • File

    A 991 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project


  • File

    A 2.00 B file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

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