SNT663.DWWH.469 (Collection)

Taxon:

Homo sapiens

Taxonomy (Entity type)

Dcc Asset:

sennet c2m2 jun26.zip

Processed File (Entity type)

Dcc:

SenNet

DCC (Entity type)

Anatomy:

adipose tissue

Anatomy (Entity type)

Persistent Id:https://doi.org/10.60586/SNT663.DWWH.469

Has Time Series Data:0

Description:This dataset was generated using the 10x Genomics Visium Spatial Gene Expression assay on a 10-μm section of fresh frozen subcutaneous white adipose tissue resected during bariatric surgery on a high-BMI (38.18) female aged 39 years. Age- and obesity-related dysfunction of adipose tissue has been linked to cellular senescence, systemic inflammation, and metabolic disease. Much remains to be discovered, however, about the spatial distribution of senescence-associated niches in human adipose tissue. 2- and 3-dimensional characterization of senescence is aided by the use of spatial omics advances such as Visium, which allows whole-transcriptome spatial profiling of RNA from tissues with 55-μm resolution. In situ reverse transcription generates cDNA molecules in the tissue, which are released, captured, and extended on spatially-barcoded oligonucleotide spots on the glass slide beneath the tissue. Barcoded cDNA is used to generate sequencing libraries, reads from which can be spatially mapped to the overlaid tissue area where each read originated.

Creation Time:2024-03-19 13:10:11.361000

Results found

Linked to

	Label	Description
	V11D13-034-A1 S1 L002 R1 001.fastq.gz File (Entity type)	A 6.13 GB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project
	V11D13-034-A1 S1 L002 R2 001.fastq.gz File (Entity type)	A 14.3 GB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project
	SNT663.DWWH.469 V11D13-034-A1.json File (Entity type)	A 556 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project
	V11D13-034 A1 fiducial.tiff File (Entity type)	A 764 MB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project
	metadata.json File (Entity type)	A 101 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project
	ome-tiff.channels.csv File (Entity type)	A 122 B file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project
	contributors.tsv File (Entity type)	A 3.36 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project
	h-and-e-metadata.tsv File (Entity type)	A 947 B file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project
	scRNAseq-10xGenomics-v3-metadata.tsv File (Entity type)	A 1.76 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project
	V11D13-034 A1.ome.tiff File (Entity type)	A 1.17 GB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

V11D13-034-A1 S1 L002 R1 001.fastq.gz

File (Entity type)

A 6.13 GB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

V11D13-034-A1 S1 L002 R2 001.fastq.gz

File (Entity type)

A 14.3 GB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

SNT663.DWWH.469 V11D13-034-A1.json

File (Entity type)

A 556 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

V11D13-034 A1 fiducial.tiff

File (Entity type)

A 764 MB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

metadata.json

File (Entity type)

A 101 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

ome-tiff.channels.csv

File (Entity type)

A 122 B file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

contributors.tsv

File (Entity type)

A 3.36 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

h-and-e-metadata.tsv

File (Entity type)

A 947 B file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

scRNAseq-10xGenomics-v3-metadata.tsv

File (Entity type)

A 1.76 KB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

V11D13-034 A1.ome.tiff

File (Entity type)

A 1.17 GB file from SenNet produced from OBI:0002631 as part of the TMC University of Minnesota Niedernhofer project

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

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Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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