Description:4DNESE2MH977: Multiplexed FISH in Sox2 tagged F123-CASTx129 with 4CBS insertions between Sox2 and SE - FKBP12(F36V) degron targeting CTCF with 12hr treatment of A485 + 6hr recovery (control) Multiplexed FISH in Sox2 tagged mouse embryonic stem cell line (F123-CASTx129) with a 7.5kb insertion containing 4 CTCF binding sites introduced between Sox2 and its Super Enhancer, treated with A485 to inhibit p300 activity for 12 hrs followed with 6hr recovery from A485 treatment.