Cell Surface Targets for Individual Cancer Patients Analyzed with Common Fund Datasets
FEATURED

Cell Surface Targets for Individual Cancer Patients Analyzed with Common Fund Datasets

Given RNA-seq samples from a patient tumor, we screen for targets which are highly expressed in the tumor but lowly expressed across all healthy human tissues in GTEx. Detailed information about the selected target are queried from several DCCs.
Cell Surface Targets for Individual Cancer Patients Analyzed with Common Fund Datasets
Mild Cognitive Impairment Use Case
FEATURED

Mild Cognitive Impairment Use Case

Find all IDG and GTEx assertions that may be related to mild cognitive impairment and any tissue type.
Mild Cognitive Impairment Use Case
Cell Surface Targets for Individual Cancer Patients Analyzed with Common Fund Datasets
FEATURED

Cell Surface Targets for Individual Cancer Patients Analyzed with Common Fund Datasets

Given RNA-seq samples from a patient tumor, we screen for targets which are highly expressed in the tumor but lowly expressed across all healthy human tissues in GTEx. Detailed information about the selected target are queried from several DCCs.
Cell Surface Targets for Individual Cancer Patients Analyzed with Common Fund Datasets
Mild Cognitive Impairment Use Case
FEATURED

Mild Cognitive Impairment Use Case

Find all IDG and GTEx assertions that may be related to mild cognitive impairment and any tissue type.
Mild Cognitive Impairment Use Case
Cell Surface Targets for Individual Cancer Patients Analyzed with Common Fund Datasets
FEATURED

Cell Surface Targets for Individual Cancer Patients Analyzed with Common Fund Datasets

Given RNA-seq samples from a patient tumor, we screen for targets which are highly expressed in the tumor but lowly expressed across all healthy human tissues in GTEx. Detailed information about the selected target are queried from several DCCs.
Cell Surface Targets for Individual Cancer Patients Analyzed with Common Fund Datasets
Mild Cognitive Impairment Use Case
FEATURED

Mild Cognitive Impairment Use Case

Find all IDG and GTEx assertions that may be related to mild cognitive impairment and any tissue type.
Mild Cognitive Impairment Use Case

All Use Cases

Explore different use cases that utilizes data from different CFDE participating programs
MW2Disease
Data Distillery Knowledge Graph

MW2Disease

For a specific disease in Metabolomics Workbench, find all IDG and GTEx assertions that may be related to the disease in a specific tissue type.
MW2Disease
Tissue2Drugs
Data Distillery Knowledge Graph

Tissue2Drugs

Find all genes that are highly expressed in a GTEx tissue and may be perturbed by a specific compound based on data from the LINCS L1000 dataset, and are known drug targets based on data curated by IDG.
Tissue2Drugs
Variant Expression in Tumor/Healthy
Playbook Workflow Builder

Variant Expression in Tumor/Healthy

We construct a joint plot showing how the variant's closest gene is expressed in tumors from KidsFirst and healthy human tissue from GTEx.
Variant Expression in Tumor/Healthy
Breast Epithelium Use Case
Data Distillery Knowledge Graph

Breast Epithelium Use Case

Find the genes that are highly expressed in breast epithelium as well as drugs that target these genes.
Breast Epithelium Use Case
Identify the Tissue Activity for a TF based on its Targets
Playbook Workflow Builder

Identify the Tissue Activity for a TF based on its Targets

Given a Transcription Factor, we collect its targets by various resources and then Enrich the set of consensus targets against GTEx Tissue expression. The result is ranked tissues potentially regulated by the transcription factor.
Identify the Tissue Activity for a TF based on its Targets
Common kinase pathways/complexes
ProKN

Common kinase pathways/complexes

Explore common pathways and complexes between kinases affected at the transcriptomics and phosphoproteomics levels by a perturbagen.
Common kinase pathways/complexes
Mild Cognitive Impairment Use Case
Data Distillery Knowledge Graph

Mild Cognitive Impairment Use Case

Find all IDG and GTEx assertions that may be related to mild cognitive impairment and any tissue type.
Mild Cognitive Impairment Use Case
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